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Showing posts with the label Antihistamine

Promethazine Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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  Promethazine  Promethazine is a medication that belongs to a class of drugs called phenothiazines. It is commonly used to treat various conditions, including allergies, motion sickness, nausea and vomiting, and as a sedative or sleep aid. Promethazine is available under various brand names, some of which include: 1. Phenergan 2. Promethegan 3. Avomine 4. Atosil 5. Prothiazine 6. Fargan 7. Sominex 8. Antinaus 9. Allersoothe 10. Phergan These are just a few examples, and the availability of specific brand names may vary depending on the country and region. Mechanism Of Action The exact mechanism of action (MOA) of promethazine is not fully understood, but it is believed to exert its effects through a combination of different actions. Here are the main actions associated with promethazine: 1.  Antihistamine:  Promethazine blocks the effects of histamine by binding to histamine H1 receptors. This action helps reduce the symptoms of allergies, such as itching, sneezing,...

Cetirizine, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications

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  Cetirizine Cetirizine is an antihistamine medication commonly used to relieve symptoms associated with allergies, such as hay fever, allergic rhinitis, and hives. It belongs to the second-generation antihistamines, which are known to cause less drowsiness compared to the older generation antihistamines. Cetirizine is available under various brand names, some of which include: 1. Zyrtec: Zyrtec is one of the most well-known brand names for cetirizine. It is available in different formulations, including tablets, chewable tablets, and syrup. 2. Reactine: Reactine is another popular brand name for cetirizine. It is available in tablet and liquid gel formula tions. 3. Aller-Tec: Aller-Tec is a brand name for cetirizine that is often available in generic forms. It is commonly found in stores and pharmacies. 4. Cetzine: Cetzine is a brand name used for cetirizine in some regions. 5. Cetrine: Cetrine is another brand name for cetirizine that is available in certain countries. It...