Fosphenytoin, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects
Fosphenytoin Fosphenytoin is a prodrug of Phenytoin , which means it is converted into phenytoin in the body. Phenytoin is an anticonvulsant medication used primarily in the treatment of seizures. Fosphenytoin is designed to be administered intravenously (IV) or intramuscularly (IM), providing a more rapid conversion to phenytoin compared to oral administration. Fosphenytoin is often used in emergency situations when rapid control of seizures is needed, as it can be administered more quickly than phenytoin. It is particularly useful when a patient cannot tolerate oral medications or when oral administration is not feasible. Fosphenytoin is primarily marketed under the brand name Cerebyx . It may also be available under other brand names in different countries. Metabolism Fosphenytoin is rapidly metabolized in the body to its active form, Phenytoin . The conversion of fosphenytoin to phenytoin occurs through the action of phosphatases, enzymes that remove the phosphate group from ...