Loratadine, Structure, Mechanism of action, Drug Interactions, Therapeutic Uses, Adverse effects and Contraindications
Loratadine Loratadine is a commonly used antihistamine medication that is primarily used to treat allergies. Loratadine is available under various brand names worldwide. Some of the common brand names for loratadine include: 1. Claritin 2. Alavert 3. Allergy Relief (generic) 4. Lorfast 5. Telfast 6. Clarityn 7. Lorinase 8. Lora-Tabs 9. Sensibit 10. Loridin Please note that brand names may vary depending on the country or region. Mechanism Of Action The MOA (mechanism of action) of loratadine involves its ability to block the effects of histamine, which is a chemical produced by the body during an allergic reaction. Here's a breakdown of its MOA: 1. Histamine release: When the body encounters an allergen, such as pollen or pet dander, mast cells in the body release histamine as part of the immune response. 2. Histamine receptors: Histamine binds to specific receptors, known as H1 receptors, located on various cells throughout the body, including those in the respiratory...